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Stem Bark Extract and Fraction of Persea americana (Mill.) Exhibits Bactericidal Activities against Strains of Bacillus cereus Associated with Food Poisoning

dc.contributor.authorAkinpelu, David
dc.contributor.authorAiyegoro, Olayinka Ayobami
dc.contributor.authorAkinpelu, F. Oluseun
dc.contributor.authorOkoh, I. Anthony
dc.date.accessioned2020-01-16T10:45:39Z
dc.date.available2020-01-16T10:45:39Z
dc.date.issued2015-12
dc.identifier.citationAkinpelu david (2015). Stem Bark Extract and Fraction of Persea americana (Mill.) Exhibits Bactericidal Activities against Strains of Bacillus cereus Associated with Food Poisoningen_US
dc.identifier.issn1420-3049
dc.identifier.urihttps://ir.oauife.edu.ng/handle/123456789/5055
dc.descriptioninternational journal of molecules, 55. p. 422-6en_US
dc.description.abstractThe study investigates the in vitro antibacterial potentials of stem bark extracts of Persea americana on strains of Bacillus cereus implicated in food poisoning. The crude stem bark extracts and butanolic fraction at a concentration of 25 mg/mL and 10 mg/mL, respectively, exhibited antibacterial activities against test isolates. The zones of inhibition exhibited by the crude extract and the fraction ranged between 10 mm and 26 mm, while the minimum inhibitory concentration values ranged between 0.78 and 5.00 mg/mL. The minimum bactericidal concentrations ranged between 3.12 mg/mL-12.5 mg/mL and 1.25-10 mg/mL for the extract and the fraction, respectively. The butanolic fraction killed 91.49% of the test isolates at a concentration of 2× MIC after 60 min of contact time, while a 100% killing was achieved after the test bacterial cells were exposed to the butanolic fraction at a concentration of 3× MIC after 90 min contact time. Intracellular protein and potassium ion leaked out of the test bacterial cells when exposed to certain concentrations of the fraction; this is an indication of bacterial cell wall disruptions by the extract's butanolic fraction and, thus, caused a biocidal effect on the cells, as evident in the killing rate test results.en_US
dc.language.isoenen_US
dc.publisherjournal of moleculesen_US
dc.subjectPersea americanaen_US
dc.subjectBacillus cereusen_US
dc.subjectantimicrobialen_US
dc.subjectpotassiumen_US
dc.subjectproteinen_US
dc.titleStem Bark Extract and Fraction of Persea americana (Mill.) Exhibits Bactericidal Activities against Strains of Bacillus cereus Associated with Food Poisoningen_US
dc.typeJournalen_US


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