Characterization of a Novel Thermostable Nuclease Homolog (Nuc(M)) in a Highly Divergent Staphylococcus aureus Clade

Schaumburg, Frieder ; Pauly, Maude ; Schubert, Grit ; Shittu, Adebayo O (2014-08)

African Research Review. 1. 10.4314/afrrev.v1i1.40988


A thermostable nuclease homologue (NucM) in an animal associated divergent clade of Staphylococcus aureus in sub-Saharan Africa has a highly divergent nucleotide sequence compared to classical nuc1 and nuc2 of S. aureus. The deduced amino acid sequences, tertiary structures nuclease activities are, however, similar.