Faculty of Pharmacy
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Effect of vernonia amygdalina delile on CYP2D6 and CYP3A4 mediated metabolism of dextromethorphan in human subjects
(Obafemi Awolowo University, 2021)The study validated an HPLC method for analysis of dextromethorphan (DEX), dextrorphan (DOR) and 3-methoxymorphinan (3-MM); and assessed the effect of Vernonia amygdalina leaf powder on Cytochrome P450 3A4 and 2D6 mediated ... -
An Evaluation of the management of primary health care services in community pharmacies in Southwestern Nigeria.
(Obafemi Awolowo University, 2021)This study identified primary health care (PHC) services offered by community pharmacists, examined management practices deployed, assessed managerial competences, analysed strengths, weaknesses, opportunities and threats ... -
Acute and repeated dose toxicity studies of aqueous extract of citrus limon(rutacea ratse) leaves in rats
(Obafemi Awolowo University, 2019)The leaves of Citrus limon has been shown to have a variety of actions such as anti-inflammatory, hepatoprotective, anxiolytic, hypoglycemic, antioxidant, febrifuge activities among others. This has largely been adduced ... -
Exchange rate fluctuation, interest rate instability and manufacturing sector output in Nigeria.
(Obafemi Awolowo University, 2019)The study appraised different interest rate policies, exchange rate regimes and manufacturing sector in Nigeria from 1986 to 2017 and determined the effect of interest rate and exchange rate interaction on manufacturing ... -
Evaluation of quality management structure in community pharmacy practice in Osun State
(Obafemi Awolowo University, 2021)This study assessed knowledge of community pharmacists about quality management structure (QMS) in Osun State, determined their attitude towards QMS, evaluated adequacy of existing QMS in CPP, and assessed impact of training ... -
Antimalaria activities of methanol extract of the combination of alstonia boonei stem Bark and picralima nitida seed in mice.
(Obafemi Awolowo University, 2020)The study determined acute toxicity of the methanol extract of the combination of Alstonia boonei stem-bark and Picralima nitida seed; determined the antimalarial activity of methanol extract of the combination; and ... -
Larvicidal Activity of Cleistopholis Patens (BENTH.) ENGL. & Diels Leaf Extract and Fractions against Culex Quinquefasciatus
(Obafemi Awolowo University, 2019)The study investigated the larvicidal activity of Cleistopholis patens leaf extract against the larvae of Culex quinquefasciatus and also determined the most active partitioned and column chromatographic fractions of the ... -
Antisickling properties of Combined Formulation of Telfairia Occidentalis HookF., Moringa Oleifera LAM. And Cnidoscolus Acontfolius Mill., As Herbal Product
(Obafemi Awolowo University, 2019)The study formulated a combined extracts of Telfairia occidentalis (TO), Moringa oleifera (MO) and Cnidoscolus aconitifolius (CA) into stable liquid dosage form (suspension), evaluated the antisickling properties, determined ... -
Assessment of Toxicity Potential of the Essential Oil of Dennettia Tripetala Seed Following Repeated Dose Administration in Rats
(Obafemi Awolowo University, 2019)The study determined the median lethal dose (LD50) of the essential oil of Dennettia tripetala G. Baker (Annonaceae) seeds in wistar rats. It also evaluated the effects of the graded doses of the oil on haematologic and ... -
Effect of Documentation Management in Community Pharmacy Practice in Osun State, Nigeria
(Obafemi Awolowo University, 2021)This study assessed the level of knowledge about documentation management among community pharmacists in Osun state, determined the attitude of the community pharmacists to documentation management in community pharmacy ... -
Anti-Stress Effects of Ethanol Extract and Fractions of the Stem-Back of Milicia Excelsa (Moraceae) in Mice
(Obafemi Awolowo University, 2020)The study determined the oral acute toxicity (LD50) and evaluated the anti-stress effects of the ethanol stem bark of Milicia excelsa (ESB) and its fractions in mice. The study also determined the most effective fraction ... -
Formulation of Aloe Schweinfurthii Gel as Oral Liquid Anti -inflammatory preparation
(Obafemi Awolowo University, 2019)The study determined the baseline physicochemical, antimicrobial and anti-inflammatory properties of the fresh gel obtained from Aloe schweinfurthii Baker (Liliaceae) leaf; carried out pre-formulation and stability studies ... -
Phytochemical investigation of COSTUS LUCANUSIANUS J.BRAUN for Larvicidal activity
(Obafemi Awolowo University, 2019)This study determined the larvicidal activity of different parts of Costus lucanusianus, the most active partitioned fraction of the most active morphological part, and the most active chromatographic fraction of the plant. ... -
Behavioural, Sedative and Anticonvulsant Activities of Essential Oil of Curcuma Aeruginosa Fresh Rhizome in Mice
(Obafemi Awolowo University, 2019)This study obtained the essential oil from the fresh rhizomes of Curcuma aeruginosa, determined the median lethal dose (LD50) and evaluated the novelty-induced behaviour, sedative and anticonvulsant effects of the oil and ... -
Formulation and Evaluation of Effervescent Granules of Parquetina Nigrescens Leaf for use as Oral Anti-anaemic Agent
(Obafemi Awolowo University, 2019)The study formulated, determined the physical properties and assessed the release properties of effervescent granules of Parquetina nigrescens leaf. These were with a view to obtaining information on the formulation and ... -
Historical appraisal of unification efforts in the Cherubim and Seraphim in southwestern Nigeria (1980-2017)
(Obafemi Awolowo University, 2019)The study traced the beginning and development of the unification efforts in Cherubim and Seraphim in Southwestern Nigeria. It highlighted and discussed the beliefs and practices of the Unification Groups in the Cherubim ... -
Evaluation of medicines inventory management in community pharmacies in Delta State, Nigeria
(Obafemi Awolowo University, 2018)Inadequate availability of essential medicines in pharmacies is an acknowledged public health problem in developing countries and many factors have been cited including poor inventory management. The objectives of the study ... -
Evaluation of the cardiovascular activities of Abelmoschus esculentus(OKRA) fruit extract and its isolated compound(s) on Rana temporaria (FROGS) heart
(Obafemi Awolowo University, 2019)The study obtained the crude extract of Abelmoschus esculentus (Okra) fruits, isolated the phytochemical compounds from the extract and elucidated the structures of the isolated compounds. It also evaluated the cardiovascular ... -
Activity- Directed Phytochemical Investigation of Spathodea Campanulata (P. Beauv)
(2015-08-06)This study investigated the crude extracts of the leaf, stem bark and flower of Spathodea campanulata for antitrichomonal, antimicrobial, molluscicidal and radical scavenging activities and the chemical composition of the ... -
Influence of Sleep Deprivation on Activities of Cytochrome P450 in Animal Behavioural Models
(5/14/2015)Sleep is a regulated state of the brain that occurs every day and has been implicated in many fundamental processes but the effects of sleep deprivation on Cytochrome P450 (CYP) enzymes have not been investigated. Thus, ...
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