Apartheid Paradigm in the Xenobiotic Biotransformation

Dixon, P.A.F (1991-05-14)


Xenobiotic biotransformation is a necessary process for the eventual elimination of the xenobiotics. This involves a functionalisation and synthetic or conjugation reactions, The pattern and degree of this biotransformation is influenced by genetic factors, species and race among many other factors, such as, age, sex, diet, stress, disease state etc. This discriminating pattern is the meat of this Inaugural Lecture "Apartheid paradigm in the xenobiotic biotransformation. Apartheid in this context has no derogatory undertone like the prevailing situation in South Africa. However, pharmacogenetic information could degenerate to such base use as the prevailing dehumanising situation in the apartheid enclave.