Department of Zoology

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Open Access
Sporadic Cryptosporidium infection in Nigerian children: risk factors with species identiﬁcation
(Cambridge University Press, 2010-08-27) TANNER, C. J.; MOLLOY, S. F.; KIRWAN, P.; ASAOLU, S. O.; SMITH, H. V.
A cross-sectional study was conducted to investigate risk factors for sporadic Cryptosporidium infection in a paediatric population in Nigeria. Of 692 children, 134 (19.4%) were infected with Cryptosporidium oocysts. Cryptosporidium spp. were identiﬁed in 49 positive samples using PCR–restriction fragment length polymorphism and direct sequencing of the glycoprotein60 (GP60) gene. Generalized linear mixed-eﬀects models were used to identify risk factors for all Cryptosporidium infections, as well as for C. hominis and C. parvum both together and separately. Risk factors identiﬁed for all Cryptosporidium infections included malaria infection and a lack of Ascaris infection. For C. hominis infections, stunting and younger age were highlighted as risk factors, while stunting and malaria infection were identiﬁed as risk factors for C. parvum infection