A Cytotoxic Indole Alkaloid from Alstonia boonei
| dc.contributor.author | Balogun, Olaoye | |
| dc.contributor.author | Ajayi, Olukayode Solomon | |
| dc.contributor.author | Agberotimi, Juliana | |
| dc.date.accessioned | 2023-05-13T18:02:31Z | |
| dc.date.available | 2023-05-13T18:02:31Z | |
| dc.date.issued | 2016-11-24 | |
| dc.description | International journal of Taylor & Francis publishing, 350p. | en_US |
| dc.description.abstract | Stem bark of Alstonia boonie (1.24 kg) was exhaustively extracted with 95 % aqueous methanol. The crude extract was defatted with n-hexane and thereafter subjected to extensive chromatography to yield Alstiboonine (1) which was fully elucidated and characterised using 2D NMR analysis. Alstiboonine, crude extract and the n-hexane fraction were subjected to brine shrimps lethality test at varying concentrations. The result showed that all the test samples exhibited significant cytotoxicity. | en_US |
| dc.identifier.issn | ISSN Print: 2231-1866 | |
| dc.identifier.issn | ISSN Online: 2231-1874 | |
| dc.identifier.uri | https://ir.oauife.edu.ng/123456789/5623 | |
| dc.language.iso | en | en_US |
| dc.publisher | Taylor & Francis publishing | en_US |
| dc.subject | Indole alkaloids | en_US |
| dc.subject | Alstonia boonie | en_US |
| dc.subject | Alstiboonine | en_US |
| dc.subject | cytotoxicity | en_US |
| dc.subject | Apocynaceae | en_US |
| dc.title | A Cytotoxic Indole Alkaloid from Alstonia boonei | en_US |
| dc.type | Journal | en_US |
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