Induction of Interferon By Poly A: Poly U in Primary Tissue Cultures.
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Date
1985
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Obafemi Awolowo University
Abstract
Primary tissue culture was grown using bat (Eidolon helvum) breast muscle. These tissue cultures were treated with polyadenylic acid: polyuridylic acid )polyA:polyU). After 24 hours the culture brew was harvested and from this, interferon was extracted and purified to a specific activity of 1.5 x 105 IFN Units/mg protein. The interferon was shown to have a molecular weight of 24,000 and fully protected bats' cells from the action of Wesselsbron Virus (H10964).
Description
133P
Keywords
Tissue, Purification, Wesselsbron Virus
Citation
Chujor, C.N (1985)Induction of interferon by poly A: poly U in primary tissue cultures.