Evaluation of Antibacterial and Antifungal Properties of Alchornea laxiflora (Benth.) Pax. & Hoffman

Simple item page
dc.contributor.authorAkinpelu, David A
dc.contributor.authorAbioye, Emmanuel O
dc.contributor.authorAiyegoro, Olayinka A.
dc.contributor.authorAkinpelu, Oluseun F.
dc.contributor.authorOkoh, Anthony I
dc.date.accessioned2023-05-13T17:45:30Z
dc.date.available2023-05-13T17:45:30Z
dc.date.issued2015-02-24
dc.descriptionInternational Journal of Evidence-based Complementary and Alternative Medicine,Page 7en_US
dc.description.abstractAlchornea laxiflora leaf extract was tested against a range of microorganisms using standard microbiological methods for antimicrobial activities. Theextract inhibited thegrowth of all thebacterial and 15fungal isolates tested. Thezones of inhibition exhibited against the test bacteria ranged between 12mm and 24mm and between 11mm and 24mm for the extract and the antibiotic streptomycin, respectively. The zones of inhibition observed against the fungal isolates by the extract ranged between 12mm and 23mm. The minimum inhibitory concentrations (MICs) and the minimum bactericidal concentrations (MBCs) exhibitedbytheextractagainsttestbacteriarangedbetween0.78mg/mL–25mg/mLand1.56mg/mL–25mg/mL,respectively,while theMICsandminimumfungicidalconcentrations(MFCs)valuesforthetestfungirangedbetween8.75mg/mL–35.00mg/mLand 8.75mg/mL–35.00mg/L,respectively.Thepreliminaryphytochemicalscreeningoftheextractrevealedthepresenceofalkaloids, tannins, flavonoids, saponins, and reducing sugars as major phytoconstituents in the extract. A. laxiflora leaf extract is a potent source of antibacterial and antifungal compounds; further studies on the extract are ongoing in our laboratories to elucidate the probablemechanism(s)ofactiononbacteriaandfungifoundtobesusceptibletotheextracten_US
dc.identifier.urihttps://ir.oauife.edu.ng/123456789/5465
dc.language.isoenen_US
dc.publisherEvidence-Based Complementary and Alternative Medicineen_US
dc.subjectAntibacterialen_US
dc.subjectAntifungalen_US
dc.subjectAlchornea laxifloraen_US
dc.subjectPax. & Hoffmanen_US
dc.subjectmicroorganismsen_US
dc.titleEvaluation of Antibacterial and Antifungal Properties of Alchornea laxiflora (Benth.) Pax. & Hoffmanen_US
dc.typeJournalen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
ECAM2015-684839.pdf
Size:
563.41 KB
Format:
Adobe Portable Document Format
Description:
Journal Article
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Journal Articles