Faculty of Pharmacy

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    Antimalarial- monitored optimisation and phytochemical investigation of mama decoction
    (Department of Pharmacognosy, Obafemi Awolowo University, 2015) Samuel Akintunde ODEDIRAN
    The study determined the optimum ratio of the combination of the component plant in an antimalarial herbal preparation, MAMA Decoction and established the most active ratio for each of the antimalarial models, also, activity-directed phytochemical investigation was carried out to determine the column fraction with the highest chemosupressive activity. This was with a view to determining the optimum combination ratio for drug development.
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    Investigation of some Nigerian ethnomedicinal antidiabetic plants forability to prevent acute hyperglycaemia
    (Department of Pharmacognosy, Faculty of Pharmacy, Obafemi Awolowo University., 2015) JAIYESIMI, Olakunle Adeboye
    The study screened nine Nigerian ethnomedicinal plants and determined the plant with the greatest ability to prevent hyperglycinemia. it also determined the most active fraction of the plant with this ability. This was with a view to providing information on Nigerian antidiabetic plants with the ability to prevent hyperglycinemia.
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    Virulence and antibiotic resistance characreristics of escherichia coli isolates from cases of infantile diarrhoea in Ile -Ife and environs
    (Department of Pharmaceutics Obafemi Awolowo University, 1998) Irukaku Nwamaka Okeke
    Eight potentially diarrhoeagenic E. will pathotypes which contribute significantly to the morbidity and mortality of young children, particularly in developing countries have hitherto been identified. Enteropathogenic, enteroxigenic, enteroinvasive, enterohaemorrhagic and enteroaggregative E. coli are definitive causes of infantile diarrhea whereas the role of diffusely adherent, cell detaching and cytolethal distending E. coli in the aetiologia of the disease is putative. E. coli is also know to harbor chromosomal and extrachromosomal genes mediating antibiotic resistance which may cause problems in the treatment of infection caused by the organism and related pathogens to which it may transfer these characters