Doctor of Philosophy (Ph.D.) Theses and Dissertations

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Virulence and antibiotic resistance characreristics of escherichia coli isolates from cases of infantile diarrhoea in Ile -Ife and environs
(Department of Pharmaceutics Obafemi Awolowo University, 1998) Irukaku Nwamaka Okeke
Eight potentially diarrhoeagenic E. will pathotypes which contribute significantly to the morbidity and mortality of young children, particularly in developing countries have hitherto been identified. Enteropathogenic, enteroxigenic, enteroinvasive, enterohaemorrhagic and enteroaggregative E. coli are definitive causes of infantile diarrhea whereas the role of diffusely adherent, cell detaching and cytolethal distending E. coli in the aetiologia of the disease is putative. E. coli is also know to harbor chromosomal and extrachromosomal genes mediating antibiotic resistance which may cause problems in the treatment of infection caused by the organism and related pathogens to which it may transfer these characters