Determination of infant's human milk intake and mother' body composition in breasfeeding mothers from Ile-Ife,using stable isotope technique

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Date
2015
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Physics and Engineering physics,Obafemi Awolowo University
Abstract
ABSTRACT This study determined human milk intake and intake of water from sources other than human milk, in breastfed babies and their mothers’ body composition at Ile-Ife using the non-invasive stable isotope method. The objectives were to determine levels of exclusive breastfeeding among the mothers, the actual amount of milk ingested by babies and also to determine the relationship, if any between maternal body composition and human milk intake. This was with a view to obtaining vital information about adequacy of milk intake for normal growth and the possibilities of transfer of pollutants to the babies through human milk. Thirty mother-baby pairs were recruited for this study. The ages of the mothers recruited in the study ranged from 19-35 years while the ages of the babies ranged from 1-9 months. Thirty milligram of sterile deuterium oxide was administered orally to each mother irrespective of the body mass and saliva samples from both mother and baby were obtained over a two-week period on days 0, 1, 2, 3, 4, 13 and 14 after the administration of the dose. Deuterium enrichment in saliva samples was determined using Fourier Transform Infrared Spectrometry (FTIR), with the deuterium absorbance peak measured between 2300-2900 cm-1. The transfer of deuterium from the mother to the baby was modeled by a multi-exponential function and the simultaneous solution of this function with a mono-exponential decay of deuterium from the mothers’ body pool was achieved using the Solver function in Microsoft Excel environment through a customized spreadsheet supplied by the International Atomic Energy Agency (IAEA). Human milk intake over the two-week study period ranged from 391 g/day to 1531 g/day. Water consumed orally other than human milk ranged from -602 g/day to 847 g/day. About 31% of the mothers practiced exclusive breastfeeding during the period of investigation .The mean maternal lean body mass was 37.9 ± 7.01 kg and the mean maternal body fat was 18.03 ± 9.87 kg. Maternal body composition varies inversely with breast milk intake (which can be assumed to be a reflectance of maternal lactation performance). This study concluded that the stable isotope technique was a precise method of determining human milk intake in breastfed babies and maternal body composition.
Description
xv, 131p
Keywords
Human milk, Breastfeeding, Breastfeeding mother, Maternal body, Isotope techniques
Citation
Ibitoye,O.O.(2015). Determination of infant's human milk intake and mother' body composition in breasfeeding mothers from Ile-Ife,using stable isotope technique.Obafemi Awolowo University
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