The antibacterial activities of some organotin compounds

Simple item page
dc.contributor.authorIyoha, Dele. E.
dc.date.accessioned2023-05-13T16:25:54Z
dc.date.available2023-05-13T16:25:54Z
dc.date.issued1985
dc.description93pen_US
dc.description.abstractNine derivatives of the organotin compound, tribenzyl tin-phenoxy acetate and an antibiotic standard, ampicillin, were tested for antibacterial potency against seven bacterial species, made up of two Gram-negative and five Gram-positive bacteria. At the screening concentration of 20mg/ml, one of the compounds, TBPA4 (Solid) - tribenzyl tin L-bromophenoxy acetale-showed no activity against any of the test organisms, while compound TBPA3-tribenzyl L-chloro phenoxy acetate-showed activity against only three of the organisms. The minimum inhibitory concentrations of the active compounds were determined and one of them, compound TBPA7-tribenzyl tin 2-nitro phenoxy acetate-showed considerable inhibitory activity against five of the organisms at a low concentration of 1ug/ml. Of the five active compounds that were subsequently used in the rate of killing experiments, TBPA7 again showed the greatest activity and it compared favourably with the antibiotic standard (ampicillin). The possibility of incorporating some of these compounds into drugs and chemotherapeutic agents, pending further tests, is discusseden_US
dc.identifier.urihttps://ir.oauife.edu.ng/123456789/5219
dc.language.isoenen_US
dc.publisherObafemi Awolowo University, Ile Ife, Nigeriaen_US
dc.subjectAntibacterialen_US
dc.subjectOrganismsen_US
dc.subjectAmpicillinen_US
dc.subjectBacteriaen_US
dc.subjectChemotherapeutic agentsen_US
dc.subjectOrganotin compounden_US
dc.titleThe antibacterial activities of some organotin compoundsen_US
dc.typeThesisen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
The antibacterial activities of some organotin compounds-M.Sc.pdf
Size:
43.55 KB
Format:
Adobe Portable Document Format
Description:
M.Sc. Microbiology
Download
License bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
M.Sc