Possible Risk factors in the occurrence of Molar-Incisor Hypomineralization among a group of Nigerian Monozygotic Twins
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Date
2015-06
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Babcock University Medical Journal (BUMJ)
Abstract
Objective
Molar Incisor Hypomineralisation (MIH) is systemic in origin, and affects one to four permanent rst molars. It frequently affects the incisors also. Its aetiology remains unknown, with some evidence suggesting association with childhood diseases during the rst four years of life, the use of antibiotics (amoxicillin, a macrolide), and exposure to dioxins. This report is documented to highlight the possible risk factors for MIH in four sets of monozygotic twins.
Methods
A case series consisting of four related case reports.
Results
Identied. This ranged from prolonged use of antibiotics, to early childhood illnesses, prenatal maternal ill health, and long duration of breast feeding.
The possibility of genes in the aetiology of MIH is further strengthened by the observation in this study, that all the monozygotic twin pairs identied with MIH during public oral health screening exercises, had the lesion.
Conclusion
The aetiology of MIH may be due to early childhood illnesses and the use of amoxicillin. Also, the possible role of genetic disposition needs to be further investigated.
Description
5p
Keywords
Citation
Oyedele, T. A., Folayan, M. O., & Oziegbe, E. O. (2015). Possible Risk factors in the occurrence of Molar-Incisor Hypomineralization among a group of Nigerian Monozygotic Twins. Babcock University Medical Journal (BUMJ), 1(2), 4-52.