Department of Child Dental Health- Journal Articles

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    Editorial: Country Profile of the Epidemiology and Clinical Management of Early Childhood Caries.
    (frontiers in public health, 2020-04-30) Folayan, Morenike Oluwatoyin; El Tantawi, Maha; Ramos-Gomez, Francisco; Sabbah, Wael
    Early childhood caries (ECC) is the presence of decayed (cavitated and non-cavitated), filled and missing teeth due to caries, affecting the primary dentition in children less than 72 months old (1). It is the most common non-communicable disease in children (2) and a global endemic problem with those socially disadvantaged (ethnic minorities, immigrants, those of low socioeconomic status or from resource-limited settings) being most affected. The negative impact of ECC on the quality of life, growth, social development, and neurodevelopment of affected children makes it ethically imperative that public epidemiological and clinical management of ECC improves (3). Whether treated or not, ECC is a high-risk factor for caries in the first permanent molar, as highlighted by Songur et al. in this topical issue. Four other manuscripts in this special issue emphasize the urgency of addressing the endemic ECC problem. Musinguzi et al. highlighted that the prevalence of ECC in rural Uganda was 48.6% in 3–5-year-olds, and Castillo et al. showed it was as high as 76.2% in 3–5-year-olds in Peru. Also, Pierce et al. reported a prevalence of 98% in some parts of Canada, and Amalia et al. reported a prevalence of 100% in South Kalimantan, Indonesia
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    Association between maternal socioeconomic factors, decision‐making status, and dental utilization by children with early childhood caries in sub‐urban Nigeria
    (American Association of Public Health Dentistry, 2020) Morenike Oluwatoyin Folayan; Micheal Alade; Abiola Adeniyi; Maha El Tantawi; Tracy L. Finlayson
    AbstractAimTo determine the association between maternal education, income, and decision‐making status and the presence of early childhood caries (ECC) and dental‐service utilization among young children.MethodsThis cross‐sectional study was based on data from a household survey of 1,549 mother‐preschool‐aged‐child dyads conducted in Ife Central Local Government Area, Nigeria. The explanatory variables were maternal education, income, and decision‐making status (related to healthcare, large household purchases, and visits to family/relatives). Outcome variables were the presence of ECC and the child's history of dental‐service utilization. Poisson regression analyses were conducted to identify factors associated with outcomes; the models were adjusted for maternal age, child's socioeconomic status, oral hygiene status, and frequency of sugar consumption.ResultsThe study recruited 1,549 mother–child dyads, of which 66 (4.3 percent) children had ECC, and 90 (5.9 percent) children had a history of dental‐service utilization. Fewer than half (42.3 percent) of the mothers earned between N18,001($49.00) and 60,000 ($168.00) per month. Also, 896 (57.8 percent) reported not making any independent decisions, 152 (9.8 percent) made one of three decisions independently, and 313 (20.2 percent) made two or three decisions independently. In the adjusted model, children of mothers with monthly income higher than N60,000 were more likely to have used dental services than were those whose mother's monthly income was less than or equal to N18,000 (adjusted prevalence ratio = 2.29; 95%CI: 1.30–4.02; P = 0.004). No other maternal factor was associated with ECC.ConclusionsAlthough maternal socioeconomic factors and decision‐making abilities were not associated with ECC prevalence, more preschool children whose mothers had high income used dental services.
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    Oral health practices and self-reported adverse effects of E-cigarette use among dental students in 11 countries: an online survey.
    (BMC Oral Health, 0022-01-26) Alhajj, Mohammed Nasser; Al-Maweri, Sadeq Ali; Folayan, Morenike O; Halboub, Esam; Khader, Yousef; Omar, Ridwaan; Amran, Abdullah G; Al-Batayneh, Ola B; Celebić, Asja; Persic, Sanja; Kocaelli, Humeyra; Suleyman, Firas; Alkheraif, Abdulaziz A; Divakar, Darshan D; Mufadhal, Abdulbaset A; Al-Wesabi, Mohammed A; Alhajj, Wadhah A; Aldumaini, Mokhtar A; Khan, Saadika; Al-Dhelai, Thiyezen A; Alqahtani, Ahmed Shaher; Murad, Ali H; Makzoumé, Joseph E; Kohli, Shivani; Ziyad, Tareq A
    E-cigarette use has become popular, particularly among the youth. Its use is associated with harmful general and oral health consequences. This survey aimed to assess self-reported oral hygiene practices, oral and general health events, and changes in physiological functions (including physical status, smell, taste, breathing, appetite, etc.) due to E-cigarette use among dental students.
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    Taking the bull by the horns: Ethical considerations in the design and implementation of an Ebola virus therapy trial.
    (Elsevier Ltd, 2016-01-01T00:00:00Z) Kombe, Francis; Folayan, Morenike O.; Ambe, Jennyfer; Igonoh, Adaora; Abayomi, Akin
    Ebola virus is categorized as one of the most dangerous pathogens in the world. Although there is no known cure for Ebola virus, there is some evidence that the severity of the disease can be curtailed using plasma from survivors. Although there is a general consensus on the importance of research, methodological and ethical challenges for conducting research in an emergency situation have been identified. Performing clinical trials is important, especially for health conditions that are of public health significance (including rare epidemics) to develop new therapies as well as to test the efficacy and effectiveness of new interventions. However, routine clinical trial procedures can be difficult to apply in emergency public health crises hence require a consideration of alternative approaches on how therapies in these situations are tested and brought to the market. This paper examines some of the ethical issues that arise when conducting clinical trials during a highly dangerous pathogen outbreak, with a special focus on the Ebola virus outbreak in West Africa. The issues presented here come from a review of a protocol that was submitted to the Global Emerging Pathogens Treatment Consortium (GET). In reviewing the proposal, which was about conducting a clinical trial to evaluate the safety and efficacy of using convalescent plasma in the management of Ebola virus disease, the authors deliberated on various issues, which were documented as minutes and later used as a basis for this paper. The experiences and reflections shared by the authors, who came from different regions and disciplines across Africa, present wide-ranging perspectives on the conduct of clinical trials during a dangerous disease outbreak in a resource-poor setting.
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    Ebola vaccine development plan: ethics, concerns and proposed measures.
    (BioMed Central, 2016-02-08T00:00:00Z) Folayan, Morenike Oluwatoyin; Yakubu, Aminu; Haire, Bridget; Peterson, Kristin
    The global interest in developing therapies for Ebola infection management and its prevention is laudable. However the plan to conduct an emergency immunization program specifically for healthcare workers using experimental vaccines raises some ethical concerns. This paper shares perspectives on these concerns and suggests how some of them may best be addressed. The recruitment of healthcare workers for Ebola vaccine research has challenges. It could result in coercion of initially dissenting healthcare workers to assist in the management of EVD infected persons due to mistaken beliefs that the vaccine offers protection. It could also affect equity and justice. For example, where people who are not skilled health care professionals but who provide care to patients infected with Ebola (such as in home care settings) are not prioritized for vaccination. The possibility of study participants contracting Ebola infection despite the use of experimental vaccine, and the standard of care they would receive, needs to be addressed clearly, transparently and formalized as part of the ethics review process. Future access to study products in view of current status of the TRIPS agreement needs to be addressed. Finally, broad stakeholder engagement at local, regional and international levels needs to be promoted using available communication channels to engage local, regional and international support. These same concerns are applicable for current and future epidemics. Successful Ebola vaccine development research requires concerted efforts at public dialogue to address misconceptions, equity and justice in participant selection, and honest discussions about risks, benefits and future access. A public dialogue about Ebola vaccine research plans is crucial and should be conducted by trusted locals and negotiated between communities, researchers and ethics committees in research study sites.