Department of Child Dental Health- Journal Articles

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    Open Access
    Stakeholders' engagement with Ebola therapy research in resource limited settings.
    (BMC Infectious Diseases, 2015-06-26T00:00:00Z) Folayan, Morenike Oluwatoyin; Brown, Brandon; Haire, Bridget; Yakubu, Aminu; Peterson, Kristin; Tegli, Jemee
    The current Ebola Virus Disease (EVD) outbreak in West Africa is the largest in history. As of February 18(th) 2015, 23,258 cases of EVD have been cumulatively reported from Nigeria, Senegal, Guinea, Liberia, Mali, Sierra Leone, Spain, the United Kingdom and the United States of America resulting in more than 9,000 deaths. It is therefore exigent to develop prevention and treatment therapies for EVD.
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    Open Access
    Non-third molar related pericoronitis in a sub-urban Nigeria population of children
    (Wolters Kluwer - Medknow, 2014) MO Folayan; EO Ozeigbe; N Onyejaeka; NM Chukwumah; T Oyedele
    The study will report on the prevalence, clinical presentation, diagnosis, and management of non-third molar related pericoronitis seen in children below the age of 15 years who report at the Pediatric Dental Clinic, Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife over a 4½ year period. This is a prospective study of cases of pericoronitis affecting any tooth exclusive of the third molar diagnosed in the pediatric dentistry out-patient clinic in Obafemi Awolowo University Teaching Hospitals Complex, Ile-Ife between January 2008 and June 2012. Pericoronitis was diagnosed using the criteria described by Howe. Information on age, sex, history malaria fever, upper respiratory diseases, tonsillitis, and evidence of immunosuppression were taken. Radiographs were taken in all cases to rule out tooth impaction and information on treatment regimen was also collected. The prevalence of non-third molar related pericoronitis was 0.63%. More females (63.6%) were affected. Chronic pericoronitis was the most common presentation (73.3%). No case was reported in the primary dentition and the premolar. No case was associated with tooth impaction and the tooth most affected was the lower right second permanent molar (35.7%). Bilateral presentation was seen in 36.4% patients. Herpetic gingivostomatitis was reported in association with one case. Chronic pericoronitis resolved within 3 days of management with warm saline mouth bath (WSMB) and analgesics, while acute/subacute resolved within 10 days of management with antibiotics, analgesics, and WSMB. The prevalence of non-third molar related pericoronitis is the low. The most prevalence type is chronic pericoronitis affecting the lower right second permanent molar.
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    Open Access
    The prevalence and pattern of deciduous molar hypomineralization and molar-incisor hypomineralization in children from a suburban population in Nigeria.
    (BioMed Central, 2015-06-30T00:00:00Z) Temilola, Oluwaseyi Dada; Folayan, Morenike Oluwatoyin; Oyedele, Titus
    Molar Incisor Hypoplasia (MIH) and Deciduous Molar Hypoplasia (DMH) have significant impact on the quality of life of affected individuals. The objective of the study was to determine the prevalence, pattern and clinical presentation of MIH and DMH in children resident in Ile-Ife, Nigeria, and their association with sex and socioeconomic status of the children. Information on age, sex and socioeconomic status was collected from 563 children aged 3 to 5 years and 8 to 10 years using a structured questionnaire through a household survey. Clinical examination was conducted to assess for the presence of DMH and MIH. The prevalence of DMH and MIH were determined. Tests of association between sex, socioeconomic status, prevalence, and pattern of presentation of both DMH and MIH were conducted using Pearson’s Chi-squared test Fisher’s exact test. Fifteen (4.6 %) of the 327 children aged 3 to 5 years and 23 (9.7 %) of the 237 children aged 8 to 10 years had DMH and MIH respectively. There were no significant association between DMH, sex (p = 0.49) and socioeconomic status (p = 0.32). There were also no significant association between MIH, sex (p = 0.31) and socioeconomic status (p = 0.41). MIH/DMH co-morbidity was observed in eight (34.8 %) of the 23 children with MIH. The mandible and maxilla were affected equally. Antimere was not observed. The prevalence of DMH and the prevalence of MIH in the study population were high. DMH and MIH were not associated with sex and socioeconomic status. There was no specific pattern identified in the presentation of DMH and MIH. The prevalence of DMH/MIH co-morbidity is also high. Patients with DMH should be screened for MIH.
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    Open Access
    Perceived Preparedness of Dental Academic Institutions to Cope with the COVID-19 Pandemic: A Multi-Country Survey.
    (MDPI, 2021-02-04T00:00:00Z) Ammar, Nour; Aly, Nourhan M; Folayan, Morenike Oluwatoyin; Khader, Yousef; Mohebbi, Simin Z; Attia, Sameh; Howaldt, Hans-Peter; Boettger, Sebastian; Virtanen, Jorma; Madi, Marwa; Maharani, Diah A; Rahardjo, Anton; Khan, Imran; Al-Batayneh, Ola B; Rashwan, Maher; Pavlic, Verica; Cicmil, Smiljka; Noritake, Kanako; Galluccio, Gabriella; Polimeni, Antonella; Shamala, Anas A; Aarheiam, Arheiam; Mancino, Davide; Phantumvanit, Prathip; Kim, Jin-Bom; Choi, Youn-Hee; Dama, Mai A; Abdelsalam, Maha M; Castillo, Jorge L; Nyan, Myat; Hussein, Iyad; Joury, Easter; Vukovic, Ana P; Iandolo, Alfredo; Kemoli, Arthur M; El Tantawi, Maha
    Dental academic institutions are affected by COVID-19. We assessed the perceived COVID-19 preparedness of these institutions and the characteristics of institutions with greater perceived preparedness. An international cross-sectional survey of dental academics was conducted from March to August 2020 to assess academics' and institutional attributes, perceived preparedness, and availability of infection prevention and control (IPC) equipment. Principal component analysis (PCA) identified perceived preparedness components. Multilevel linear regression analysis assessed the association between perceived preparedness and fixed effect factors (academics' and institutions' attributes) with countries as random effect variable. Of the 1820 dental academics from 28 countries, 78.4% worked in public institutions and 75.2% reported temporary closure. PCA showed five components: clinic apparel, measures before and after patient care, institutional policies, and availability of IPC equipment. Significantly less perceived preparedness was reported in lower-middle income (LMICs) (B = -1.31, = 0.006) and upper-middle income (UMICs) (B = -0.98, = 0.02) countries than in high-income countries (HICs), in teaching only (B = -0.55, < 0.0001) and in research only (B = -1.22, = 0.003) than teaching and research institutions and in institutions receiving ≤100 patients daily than those receiving >100 patients (B = -0.38, < 0.0001). More perceived preparedness was reported by academics with administrative roles (B = 0.59, < 0.0001). Academics from low-income countries (LICs) and LMICs reported less availability of clinic apparel, IPC equipment, measures before patient care, and institutional policies but more measures during patient care. There was greater perceived preparedness in HICs and institutions with greater involvement in teaching, research, and patient care.
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    Ethics and HIV prevention research: An analysis of the early tenofovir PrEP trial in Nigeria.
    (WILEY, 2018-09-10) Peterson, Kristin; Folayan, Morenike O
    In 2004, the first ever multi-sited clinical trials studied the prospect of HIV biomedical prevention (referred to as pre-exposure prophylaxis-'PrEP'). The trials were implemented at several international sites, but many officially closed down before they completed. At most sites, both scientists and community AIDS advocates raised concerns over the ethics and scientific rationales of the trial. Focusing on the Nigerian trial site, we detail the controversy that emerged among mostly Nigerian research scientists who scrutinized the research design and protocol. While some of the disputes, especially those pertaining to community engagement mechanisms, were ultimately resolved in international fora and implemented in later PrEP trials, concerns over science rationales and assumptions were never addressed. We argue that scientific rationales should be treated as ethical concerns and suggest that such concerns should be deliberated at host sites before the trial protocol is finalized.